And the winner is. . .

i-49a0614e6c76937b3e7cd49ae84b2904-Propofol structure.jpg


For further information and detailed background, please see our previous post on this injectable anesthetic agent known as propofol or Diprivan®.

This L.A. Times article today also has a concise timeline of the events leading to the death of Michael Jackson

More like this

Judging from the press inquiries I've had since 5 am EDT today, expect today's focus in the Michael Jackson case to be on the anesthetic drug, propofol (Diprivan®). Last evening, California nutritionist and registered nurse Ms Cherilyn Lee gave an interview to Campbell Brown on CNN (and this AP…
While invoking my little-known real name, the ABC News Medical Unit shows its commitment to providing scientifically-objective and medically-valid commentary to the Michael Jackson circus. The post cited was from 26 June where I discussed the first Michael Jackson revelation that he had repeatedly…
Since I abhor the entombment of real news beneath the Michael Jackson story, I didn't think I'd be posting about it, but here I am. You see, Jackson was reportedly under the "care" of a privately hired physician when he died, and was being treated with medications not normally used outside the…
AOL's celebrity gossip page was first yesterday to report Michael Jackson's death, in part due to their direct line to one or more Jackson family members. They appear to have had another scoop today in referencing a family member who reported that Mr Jackson had received an injection of the…

Conrad Murray, Jackson's personal doctor, told detectives with the Los Angeles Police Department that he had been treating Jackson for insomnia for about six weeks. He had been giving Jackson 50 milligrams of propofol every night using an intravenous line, according to the court records.

But Murray told detectives that he feared Jackson was forming an addiction and began trying to wean the pop star off the drugs. He lowered the dosage to 25 milligrams and mixed it with two other sedatives, lorazepam and midazolam. On June 23, two days before Jackson's death, he administered those two medications and withheld the propofol.

On the morning Jackson died, Murray tried to induce sleep without using propofol, according to the affidavit. He said he gave Jackson valium at 1:30 a.m. When that didn't work, he said, he injected lorazepam intravenously at 2 a.m. At 3 a.m., when Jackson was still awake, Murray administered midazolam.

Over the next few hours, Murray said he gave Jackson various drugs. Then at 10:40 a.m., Murray administered 25 milligrams of propofol after Jackson repeatedly demanded the drug, according to the court records.

Holy. Crap.

By DrugMonkey (not verified) on 24 Aug 2009 #permalink

the rebuttal:

"Much of what was in the search warrant affidavit is factual," attorney Edward Chernoff said in the statement. "However, unfortunately, much is police theory. Most egregiously, the timeline reported by law enforcement was not obtained through interviews with Dr. Murray, as was implied by the affidavit. Dr. Murray simply never told investigators that he found Michael Jackson at 11:00 a.m. not breathing. He also never said that he waited a mere 10 minutes before leaving to make several phone calls. In fact, Dr. Murray never said that he left Michael Jackson's room to make phone calls at all."

By DrugMonkey (not verified) on 25 Aug 2009 #permalink