Ready for this week's mystery campus?
What could it be? A space ship?
Some things heard from it's interiors:
"It's not protein, it's some other filtrate that transforms them."
"Let's just fire a bunch of electrons at the cell and see what we get."
"The proteins must contain a signal."
Where is this? Who are these people? What are they talking about?
Leave your proposals in the comment section.
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For this week's OAS Wednesday, I thought I'd try to highlight some research that's in my field. As a result, I will likely be more prone than usual to lapsing into jargon and assuming knowledge that I shouldn't (or maybe I'll over-correct and get too simplified). Please let me know if anything…
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The Discovery Institute doesn't understand the protein folding problem. I mean that literally: they don't understand the problem. Scientists don't know the answer, but they have a clear understanding of the problem.
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DNA was discovered to be the agent of inheritance by Oswald Avery of Rockefeller University, along with Colin MacLeod and Maclyn McCarty, in 1944.
The dome displayed is along York Ave, between E 66th and E 67th St.
This is the Caspary auditorium at Rockefeller University. Home of the two Nobel Laureates mentioned in the entry:
George Palade, who pioneered the use of the electron microscope to look inside the cell. The founder, together with Albert Claude, Christian de Duve and Keith Porter, of modern cell biology.
Gunter Blobel, who identified signal sequences that target proteins to different regions in cells.
So what do I win?
The pleasure of being first.
It's funny on the old scavengergoogle blog (where I got the idea from), the winner would get a vintage postcard mailed to his home address. I don't have anything to give ... I guess I could mail you an old over-exposed film of a failed western blot, but some how I don't think that it would make a nice prize.
And like, who doesn't have a closet full of those anyway?
Here's a paper I'd like you to analyze in your spare time:
The RNA/Protein Symmetry Hypothesis: Experimental Support for Reverse Translation of Primitive Proteins
MASAYUKI NASHIMOTO,
Journal of Theoretical Biology, Volume 209, Issue 2 , 21 March 2001, Pages 181-187.
It is completely wrong, but very thought provoking.
Funny, a couple of days ago someone for Szostak lab told me about this theory. I'll have to look at it ...