Long lab day

It's incredible. You finish with one project, and the next set of experiments pops up. No time to blog, no time to read papers ... although there are several interesting ones: transcriptional regulation by an endogenous antisense RNA in yeast, ribosomes composed of slightly different subunits translate different messages, how the endoplasmic reticulum is inherited in yeast and how this act helps organize the septins, and this very complicated paper about the energetics of protein folding and how this relates to vesicular transport. If anyone has had the time to sift through these, please let me know what you think.

Thanks,
Overworked (lazy) postdoc

Tags

More like this

No soccer today. So instead of spending time watching others run around, go read the two papers, published in last week's Nature on Golgi maturation. Proteins that need to traverse, or be embedded, within membranes are synthesized on the surface of the endoplasmic reticulum (ER). At the ER…
Here I am, in the lab with one last experiment to go before I leave to feast on a Christmas Eve dinner, so while I wait for that last centrifugation step, I'll write a quick post about all these great papers on RNA Polymerase II and chromatin remodelling. As I've said before, if you want to…
I've written much about the Nuclear Pore Complex (NPC). This large molecular gate controls the flow of molecules into and out of the nucleus. Recent work (see this post and this new paper) describes how filaments containing "FG repeats" form a matrix in the center of the pore that blocks the…
So in previous posts I've written: How to think about biology, Life is full of machines and Life and information. I guess I'm on some philosophy of Biological study kick. Now I'll put the pieces of the puzzle and talk about what those proteins encode in the typical mammalian organism. This will go…

Alex- I know that you are busy in the lab, but could you answer a few questions for me?
1- How importnat is it to record data from my experiments and labs?
2- What kind of notebooks should I use?
3- Where should I buy a notebook? (The notebooks in the campus bookstore suck! I have searched on the internet and the only books that I like are the duplicator notebooks and those can get a little pricey.)
Thank you!

1- very important!
2- hand written old style or computer - it doesn't matter. As for computer there are some commercial software out there, or you can use a wiki if you are brave (in which case you should ask Pam Silver's or Jean-Claude Bradley's lab what they use.) You can even use MS Word - however figures and excel graphs don't interface well with Word. The husband of a colleague of mine was working on software for computer style notebooks - but I'm not sure how far he got before he had to switch.
3- If you opt for the old fashion method - anywhere you can find a regular notebook whose pages are large enough to accommodate gels, printouts etc. The books we use are from Avery Dennison (computational notebook 43-648 11 3/4" x 9 1/4")