There are all too few roman a clefs for life in modern academia
Changing Places, of course, and its sequels by Lodge; Smiley's Moo; and the classic, if dated, History Man by Bradbury.
(I'm tempted to add in the Rachel Papers by Amis but I won't.)
Now the legendary pseudonymous Female Science Professor has compiled some of her favourite blog entries into a (self-published) book, thereby attempting to prove that there really are some true gems in the self-publishing industry.
I have not read it, yet, but I am assured it must be good.
You just know it has to be good.
Yes, it really will be like "Moo" meets Medawar's "Advice to a Young Scientist".
But, who should be cast for the movie?
Moo may be listed as a novel but as you suggest here is a must-read for newbie assistant professors. A real instruction manual for professorial careers...
Jodie Foster, of course!