John Hawks on introgression

The whole post is worth reading, but the money shot:

The central point of the paper is exceedingly simple. Haldane demostrated in 1927 that the fixation probability of a single copy of a new adaptive allele is 2s. This means that if archaic humans had any alleles that would have been adaptive for modern humans, it would take only a very small amount of interbreeding for modern humans to pick up these alleles, with a near-100 percent likelihood.

Greg Cochran has more. Obviously this work builds upon the Lahn introgression paper. Instead of crude species typologies the data is now pointing to a more complex set of relations between gene lineages.

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Update: Update at the bottom.... In reference to the sequencing of the Neandertal genome, Kambiz at Anthropology.net states: I have one little gripe with the New York Times article. Wade quotes a geneticist, Dr. Bruce Lahn saying there is, "evidence from the human genome suggests some…
About a month ago I posted quite a bit about Neandertal introgression into modern humans. That is, the uptake of Neandertal alleles are a few specific adaptively salient loci even while ancestry remains predominantly African. Now John Hawks and Gregory Cochran have a new paper out, Dynamics of…
I've been talking about introgression for a year right now. I've been waiting for the papers on this topic to come out, and the first has. If you haven't, please read the posts from Greg and John Hawks. Another paper is on the way, and Hawks promises something within this week. I strongly…
Update II: Follow up post. You really should read Greg and John Hawks, seeing as how they have a paper in the pipeline on this topic which is stepping off from where Lahn et. al. left off. Update: Greg and John Hawks have much more must read stuff! Read about it here. Here is the paper, Evidence…

Aha, so there's a forthcoming article on specific loci! Guess my question in the comments at the GNXP post will have to wait a little longer to be answered...

Builds upon, but not originally inspired by. Thoughts about that 2s effect were worked out in 2001: germ of the idea, in 1998, maybe earlier. Save your email.

That's two posts in a row with the phrase "money shot." Where are you picking up this lingo?

By Mustafa Mond, FCD (not verified) on 19 Dec 2006 #permalink