A Good Diagram of How Antibiotic Resistance Evolves

One of the little things I liked about Rick Weiss' cefquinome article was a diagram about how antibiotic resistant strains evolve.

One of the confusing things about the evolution of resistance (and natural selection, for that matter) is the notion that the evolution of resistance happens among individuals within populations. This graphic from the Washington Post lays that out quite nicely:

GR2007030500018

It might be good for students too.

More like this

Yes, this is O157:H7, not ExPEC. Bully for you.
While many laboratory experiments have shown that antibiotic resistance imposes a fitness cost on resistant bacteria, it's far less clear if this is the case in natural populations.
Yesterday, four people emailed me, asking about Brian Palmer's Slate article about antibiotic resistance. Since I'll probably get more such emails (and thank you for sending them), I'll offer my thoughts below:
I've written before about antibiotic resistance in the developing world.

Steven,

yes, but the rate of plasmid transfer is usually very low, so, in effect, it should be thought of as a funky kind of mutation. In other words, plasmid transfer isn't infectious, in the way that a virus is.

As with all things in biology, there are obviously exceptions.

There are chemical signals that increase the rate of plasmid transfer. I don't know if antibiotics have this kind of effect, but I wouldn't be surprised if some do.

(I used to work on this - except the transfer was from bacteria to plants.)

There are chemical signals that increase the rate of plasmid transfer. I don't know if antibiotics have this kind of effect, but I wouldn't be surprised if some do.

There are chemical signals that increase the rate of plasmid transfer. I don't know if antibiotics have this kind of effect,

I recall reading an article that said the opening shots in the next world war would be in cyberspace, with dodgy spambots flooding the net.

Either that or its viral marketing.

One of the confusing things about the evolution of resistance (and natural selection, for that matter) is the notion that the evolution of resistance happens among individuals within populations. This graphic from the Washington Post lays that out quite nicely:

good job..

I recall reading an article that said the opening shots in the next world war would be in cyberspace, with dodgy spambots flooding the net.