Placidyl (Rehnquist relaxant)

Last week it was revealed that for just about the entire 1970's, former SCOTUS chief justice Rehnquist was taking Placidyl. This is too long by any measure - it's been unavailable in the States for almost a decade (due to better alternative supplanting it), and even when it was available, it was thought to be less-than-prudent to prescribe it for more than a week. Further, he was taking about triple the recommended dose. He went through some ugly withdrawal symptoms, in one case insisting that the CIA was plotting against him.

# InChI: InChI=1/C7H9ClO/c1-3-7(9,4-2)5-6-8/h1,5-6,9H,4H2,2H3/b6-5+

It is hard to overstate the importance of the benzodiazepines in modern medicine. Xanax, Valium, Rohypnol, Klonopin - they are all benzodiazepines, and they are the "minor tranquilizers" you see all the time now. Not to say they're completely safe, but they have side effect profiles we're a bit better at predicting than some of the stuff we were taking as recently as 20 or 30 years ago.

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Hallucinatory paranoia is rational acceptance of a toxic society. The very bestest psychopharmaceutical remediation is Paxil. Not only does it rapidly transform an 85-year old whining bitch into a maleable semi-vegetable, it is intensely addictive. Lil' Miss Sweetness and Light will stay that way, beg to stay that way, "gimme the pill!"

Next best are lipophilic statin cholesterol anti-anabolites. Brain white matter is 30 wt-% cholesterol. Leach neuron-insulating non-saponifiable lipid from the skull and transform every fascist capitalist Baby Boomer into a drooling socialist Alzheimer-Democrat. Pelosinate America!

It's hard to beleive that he wasn't being poisoned by an actual plot -- a consipiracy of one (his doctor). Even then long term usage of the drug was contraindicated.