Getting your R01 funded

Why am I making all this fuss over the latest stats on acceptance rate of general RO1 grants distributed by the National Institute of Health (NIH) ? This is the money that keeps the biomedical/life sciences alive in the US. The numbers indicate that fewer grants are aproved on the first submission. To get your grant funded, you have to resubmit more and more. The longer it takes to get your grant approved, the more your career is in jeopardy. Every time your grant request is turned down, it's another 3-4 months until you can resubmit it to the NIH. If you spend all your time writing and submitting grants, you can't get any new work done. Here are more stats on the types of grants approved (generously compiled and donated by PhysioProf):

i-5137ec39ffd98ec4878c85bb438ab736-resubmisssion.jpg

Over the years, the NIH has been accepting more and more grants that have been round the bend 2-3 times. What a waste of time for all those involved. As Mike has mentioned, this is a minor nuisance for senior researchers, but a career-threatening burden to junior professors. On top of that senior scientists have the manpower to bolster their grants with new data with every resubmission, thus these resubmitted grants are backed by additional "preliminary results". Junior faculty don't have this luxury. (And if your "preliminary data" includes several papers which fulfill half of your aims, is the data still "preliminary"?) The NIH needs to adjust its priorities to help junior faculty - or else risk killing off promising new labs with all their potential to explore new fields and develop new technologies.

Tags

More like this

It looks as though I've been tagged by Drug Monkey, who apparently thinks that I might have something worth saying about the state of the NIH and its peer review system, about which the NIH is presently soliciting comments, as pointed out to me by Medical Writing, Editing, & Grantsmanship. Why…
As an NIH-funded surgeon/scientist, I just had to read this report at BrokenPipeline.org when I became aware of it, courtesy of Bora and Drugmonkey. Basically, it describes how bleak the NIH funding situation has become, particularly for young investigators. The report (PDF) comes from several…
For those of you not in the biomedical sciences, you may not be aware of the coming crises. Right now aspiring postdocs and new independent investigators are involved in a war of attrition when it comes to funding. How did this happen? Well as the NIH budget grew in the 1990s, PIs simply used the…
As I mentioned before, I was at the American Association for Cancer Research Meeting in Los Angeles last week. During the meeting, I happened to attend a plenary session talk by the Director of the National Cancer Institute (NCI), Dr. John Niederhuber, whose topic was the rather dire NCI funding…

Alex,

that's a great point. When roughly 60% of accepted R01s are resubmissions, it screws everything up.

A very good point.....writing revisions of grants all the time takes a lot out of not just the PI, but the students involved as well (particularly in small labs). And I know junior PI's who got very good scores (10 percentile in their first review), who had to resubmit them twice! That's getting to be absurd. In one RO1 case (a renewal for a young faculty just tenured), the second review came back with no comments and a ~9 percentile, but they still had to submit it a third time.

Talk about tough times.

Someone asked me how this was compiled. Here is what PysioProf wrote to me:

I obtained the data by searching CRISP for new grants awarded each year containing "-01", "-01A1", or "-01A2" suffixes in the grant number. The 2006 fiscal year data are current as of May of this year.

It would be interesting to see this graph overlaid with the number of new biomedical PhDs awarded per year.

About the preliminary data that covers half the specific aims? We call it retroactive funding, I don't know how it's referred to up there.