Yes I've been neglecting my blog

This week I've spoken too much (I got to pitch my work to a couple of visiting seminar speakers), but written so little, so in some cosmic way my total quota of verbal diarrhea has been met. On top of that I haven't read a single paper in the last two weeks ... I've glanced at a few, but not really sat down and read. I haven't even flipped through the journals to see what's out there. Anything cool recently? (In the realm of cells and cellular biochemistry?)

I haven't even thought about Map that Campus, although I'm tempted to place that feature on hiatus and start a new Friday feature. Any suggestions?

So what have I been doing? Sequence gazing. An activity akin to numerology. Lots of ATGC, lots of EEEEEEEEEEE and LLLL, and other weird stuff, and yes some insight, but you'll have to wait for the publication to read about what's hiding in our genome. All I'll say is that its the wet experiments that told us that something is there. So to all those sequence gazers, through bench work you can gain much insight into what is actually in the genome.

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About a week ago, I offered to answer questions about subjects that I've either worked with, studied or taught. I haven't had many questions yet, but I can certainly answer the ones I've had so far. Today, I'll answer the first question: How do you sequence a genome? Before we get into the…
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well this is neither cell biology or biochemistry, but recent aop in nature from the Lewis Kay lab [Sprangers and Kay, 2007] shows how NMR can be used to look at molecular dynamics of the 670kDa 20S proteosome... considering this technique has an usual upper limit of 35 - 50kDa for structure solving, this is pretty cool.

And no i'm not a structural biologist, just like to keep my options open...

I haven't even thought about Map that Campus, although I'm tempted to place that feature on hiatus and start a new Friday feature. Any suggestions?

How about Name that Building on the Northwestern Campus? I could send you a few images to start it off.

By Mustafa Mond, FCD (not verified) on 26 Jan 2007 #permalink

Sequence of the week? (ZZZZZzzzzz)

Re: MTC. If you post it I'll answer it.

By Acme Scientist (not verified) on 26 Jan 2007 #permalink

Mustafa - Okay, I'm in...

Alex - How about a weekly feature: Debunk That ID Myth? To be an IDer is to be a lier, and they are always pretending to know science, when they don't know jack. The DI (Discovery Intitute)would hate it if you added to their woes through a little hard-core transcription slammage. My $.02 and worth every penny of it.

Wesley Elsberry plays Debunk that ID Myth. ID shill Cornelius Hunter presents a slide at an ID conference illustrating the similarity between wolves and thylacines (marsupial wolves). But wait: it's actually two copies of the same image! When Wesley points this out, Hunter does not quite confess, instead he uses the opportunity to accuse evolutionists of ignoring the science. Wesley hangs him out to dry.

By Mustafa Mond, FCD (not verified) on 27 Jan 2007 #permalink