Medicine
gregladen | April 17, 2009From a Michigan State University Press Release:
A Michigan State University researcher has developed a working vaccine for a strain of E. coli that kills 2 million to 3 million children each year in the developing world.
Enterotoxigenic E. Coli, which is responsible for 60 percent to 70 percent of all E. coli diarrheal disease, also causes health problems for U.S. troops serving overseas and is responsible for what is commonly called traveler's diarrhea.
A. Mahdi Saeed, professor of epidemiology and infectious disease in MSU's colleges of Veterinary Medicine and Human Medicine, has applied…
mikethemadbiologist | April 17, 2009A recent article in MMWR Weekly with the unassuming title of "Preliminary FoodNet Data on the Incidence of Infection with Pathogens Transmitted Commonly Through Food --- 10 States, 2008" is incredibly disturbing.
The incidence of reported (more about that in a bit) Salmonella was 16.20 cases per 100,000 people. If we use a population size of 300 million, that means (Mad Biologist takes off shoes to do big number arithmetic) roughly 48,600 people had food associated Salmonella infections.
But it's probably higher than that, although I have no idea how much higher. For a Salmonella infection…
grrlscientist | April 15, 2009tags: performance horses, polo, racing, tendon injury, stem cell research
Horses clear a jump during the Challenge Cup Handicap Steeplechase
on the second day of the Cheltenham Festival in the UK.
Image: BBC News.
Those of you who follow my writings about racehorses and other high-performance horses will be interested to learn that several companies that I've been following have been redirecting their stem-cell research that they originally developed to help injured horses to help people recover from Achilles tendon injuries.
After a tendon or ligament tear, both horses and people…
palmd | April 15, 2009First, I'd like to thank everyone who participated in the naturopaty primary care challenge. It was far more successful than I could have hoped. A number of naturopaths and their supporters responded, most of them quite rationally. It takes guts to walk into the fire.
It also takes fanaticism.
I have always rather assumed that most naturopaths and other "alternative" healers are, on the whole, motivated by good. After reading all the comments, I still hold that assumption---most "alternative" healers probably mean well. That does not, however, divorce them from an ethical…
revere | April 15, 2009The Wall Street Journal (WSJ) calls it a "reality check," meaning, in their terms, a check against the mistaken idea that there is more foodborne illness these days. That's one way to look at it. Another is a look that is reality based. The reality is that there is a tremendous health burden from tainted food that is unaddressed, at least going by the same CDC Morbidity and Mortality (MMWR) report the WSJ was citing. MMWR was reporting on 2008 data from FoodNet on the incidence of infection from enteric pathogens commonly transmitted via food:
Despite numerous activities aimed at preventing…
dgmacarthur | April 13, 2009Mark Henderson has a great piece in the Times exploring the impact of personal genomics on the practice of medicine.
The basic theme should be familiar to anyone who has been following the emergence of the personal genomics industry: doctors are currently almost completely unprepared for the onslaught of genetic information they are about to experience. Here's the situation:
At present, genetic training focuses on Mendelian diseases - rare mutations in
single genes, which usually have severe effects. People who inherit the
Huntington's mutation, for example, will invariably develop the…
jstemwedel | April 11, 2009One arena in which members of the public seem to understand their interest in good and unbiased scientific research is drug testing. Yet a significant portion of the research on new drugs and their use in treating patients is funded by drug manufacturers -- parties that have an interest in more than just generating objective results to scientific questions. Given how much money goes to fund scientific research in which the public has a profound interest, how can we tell which reports of scientific research findings are biased?
This is the question taken up by Bruce M. Psaty in a Commentary…
terrasig | April 10, 2009Congratulations are going out today to Duke women's basketball guard and Coloradan, Abby Waner, on her no. 21 selection in yesterday's WNBA draft. A solid competitor, leader, and scholar, Waner was the 2nd pick by the New York Liberty. A Highlands Ranch (CO) ThunderRidge High School standout and Colorado Sports Hall of Fame inductee, Waner contributed over the last four years to Duke's NCAA Tournament appearances, including the 2006 finals when Duke lost to Maryland in a heartbreaker.
The entire Waner family holds a special place in our hearts. Extending a little Southern hospitality to…
terrasig | April 9, 2009
A recent business sojourn to Key West, FL, gave your intrepid blogger (who still has yet to set up his own CafePress swag shop) an opportunity to revisit a story we first discussed in February of an acupuncturist being arrested on three felony charges for obtaining controlled substances by forgery. Commenter ebohlman noted at the time the address of the acupuncturist's practice:
Duck Avenue? Is that where all the quacks have their practices?
While I expressed some sympathy for the practitioner if she were addicted to narcotics, I also feared that she might have used some of the drugs to…
jstemwedel | April 8, 2009The Independent reports that drug giant Pfizer has agreed to pay a $75 million settlement nine years after Nigerian parents whose children died in a drug trial brought legal action against the company.
It's the details of that drug trial that are of interest here:
In 1996, the company needed a human trial for what it hoped would be a pharmaceutical "blockbuster", a broad spectrum antibiotic that could be taken in tablet form. The US-based company sent a team of its doctors into the Nigerian slum city of Kano in the midst of an appaling meningitis epidemic to perform what it calls a "…
pharyngula | April 8, 2009She's so mad about how mean pro-choice people are, that she's making up new facts. She says she received death threats over her callous use of the death of children, which may be entirely true (and if it is, I'm pissed off at you: no, it doesn't matter how vile her behavior is, you don't threaten physical harm over it), but she also makes strange claims about how harmless the raving loonies of the anti-choice movement are. Part of it is fallacious context. The anti-choicers haven't blown up as many buildings as the number of churches that have been burned down! (Never mind that there is no…
sb admin | April 7, 2009by Alison Bass (cross-posted)
Martin Keller is finally stepping down as the long time chief of psychiatry at Brown University. Brown University officials made the announcement in a Dear Colleagues letter dated today from Edward J. Wing, Brown's new Dean of Medicine and Biological Sciences.
While Brown officials insist that the decision to step down was Keller's, my understanding from several sources is that the university has been under pressure to take action ever since Side Effects was published last June and Sen. Charles Grassley began investigating Keller's undisclosed conflicts of…
j7uy5 | April 7, 2009The American Psychiatric Association is considering whether to
href="http://www.nytimes.com/2009/04/05/magazine/05wwln-safire-t.html">reboot
their diagnosis machine. In 1952, the Diagnostic and Statistical
Manual (DSM) was published. In 1980, the third edition was
published. The third edition was important, because for the first
time, it required the use of specific criteria for establishing a
diagnosis. (See
href="http://www.newyorker.com/archive/2005/01/03/050103fa_fact">this
New Yorker article for a description of the history of DSM and the
development of the descriptive…
oracknows | April 7, 2009Note the followup post to this one, in which Orac admits error. You just have to read it, given how rarely Orac messes up when speculating...
Our cancer center has a large, open area interspersed with patient waiting areas, one of which is the clinic where I see patients, that I frequently must traverse to get to the elevators that will take me to my lab. In each patient area is a large-screen television to help patients pass the time during the inevitable wait to be seen by their doctors. As I happened to be wandering through that area on the way to my lab and office, I noticed on one of…
revere | April 5, 2009My public health colleague DemFromCT continues his public health interview series on the front page of DailyKos today, talking to Dr. Georges Benjamin, Executive Director of the American Public Health Association (APHA). Dem clearly likes Dr. Benjamin, which is not a surprise. He is a very likable person. I have been a member of APHA (on and off; I keep forgetting to renew) for over 40 years, have served on one of its top policy boards and been a member of its Governing Council. But in recent years I have had little to do with APHA, and Dem's interview today illustrates one of the reasons.…
scientificactivist | April 5, 2009As mentioned here previously, the stimulus package passed in February includes funds to encourage evidence-based medicine. Some uninformed critics will claim that this is some big government conspiracy to exert socialized control over private medicine. But, truly, encouraging a firmer empirical basis in all aspects of medicine--through more studies, government guidelines, and just improved common practice--is a very desirable outcome.
A post by David Newman at The New York Time's Well blog lays out a variety of examples of why this is so (with links to original studies!). Also, Hugh Pickens…
pharyngula | April 4, 2009
Uh-oh. There is evidence that the damning email might have been faked. The "from" field of the message looks to have been crudely pasted in, and this whole story may be a product of a slighted student's imagination.
This is an astonishing example of homophobic bigotry in a nursing college. A student was basically flunked out of a key course in the curriculum for a reason you will find hard to believe — here's a letter from a nursing faculty member to the student:
Nioska, I've been thinking about the meeting in rita's office and I feel that maybe Nursing is the wrong career for you. As a…
neurophilosophy | April 1, 2009It is now well established that the adult mammalian brain contains stem cells which continue to generate new neurons throughout life. This discovery, and subsequent research, has transformed the way we think about the brain. It is, for example, known that physical and mental exercise can stimulate the growth of new nerve cells in a part of the brain which shrinks in Alzheimer's and depression, and so it is believed that such activities can reduce the risk of both conditions.
Despite all this, little is known about the mechanisms by which neural stem cells are directed to generate neurons.…
purepedantry | March 31, 2009Nature Clinical Practice Neurology has a salient article on ethics and medicine. The article asks the question: is it ethical to confront an individual with whom you do not have an official doctor-patient relationship, if you think they have a medical problem? Should you or should you not tell them if you see a medical problem?
Neurology is unique among the medical specialties in that much of the clinical examination can be appreciated visually and taught by use of video recordings.3, 4 Since 2003, we have conducted a 'neurological localization course', during which participants are…
tqa | March 31, 2009
Your sink is leaking all over your bathroom floor. Whose advice do you take on how to fix it - your plumber's or your accountant's? I suspect that the sane among us would typically go to the plumber. If we were suspicious about the first plumber's advice, we'd probably call another plumber. Similarly, the rational among us would not look to a plumber as a source for informed commentary on the economy, foreign affairs, or journalism.
We understand that expertise matters.
We don't consider experts to be infallible, we don't bow down and worship at their feet, or uncritically accept…