Medicine
gregladen | February 7, 2009An investigation by the Sunday Times (UK) indicates that the doctor who reported information suggesting a link between MMR vaccine and autism may have "misreproted results in his research." The investigation purpots to show that ...
...Andrew Wakefield manipulated patients' data, which triggered fears that the MMR triple vaccine to protect against measles, mumps and rubella was linked to the condition.
The research [originally] claimed that the families of eight out of 12 children attending a routine clinic at the hospital had blamed MMR for their autism, and said that problems came on…
cortex | February 7, 2009One of the case studies I use in How We Decide when discussing the dangers of information overload concerns the diagnosis of back pain. Before the introduction of MRI's in the late 1980s, doctors were forced to rely on X-rays when diagnosing back pain. X-rays provide doctors with a limited amount of information, since they only reveal the bones and spinal column. As a result, back pain remained a mostly mysterious phenomenon, and most patients were prescribed bed rest. Nevertheless, this simple treatment plan was still extremely effective. Even when nothing was done to the lower back, about…
clock | February 6, 2009This month's Science Cafe (description below) will be held on February 17th at The Irregardless Cafe. We will be meeting Dr. Yvette Cook from the Rex Hospital Sleep Disorders Clinic. She will be talking with us about sleep patterns and why people may have trouble getting a good night's sleep. I have attached an article Dr. Cook recently wrote for a Rex Healthcare newsletter that you may find of interest. I hope that many of you can come - it should be a very interesting and informative discussion.
Sleep and Sleep Disorders
Tuesday, February 17, 2009
6:30-8:30 pm with discussion beginning…
denialism | February 6, 2009
What do this cartoon and the latest edition of PLoS One have in common? Well, reading Bora's blog this week I saw an article entitled, Risks for Central Nervous System Diseases among Mobile Phone Subscribers: A Danish Retrospective Cohort Study and my ears perked up. We have been mocking the idea that cell phones cause everything from brain cancer to colony collapse disorder and it's always fun to see what cell phones are being blamed for based on weak associations and correlations.
In this article the authors identified more than four hundred thousand cell phone subscribers and linked…
oracknows | February 6, 2009
I realize that I've been neglecting my woo. Indeed, yesterday I noticed that it's been a month and a half since I did a real Friday Dose of Woo. Of course, that particular installation of my long-running blog series (over two and a half years!) was some incredibly powerful woo. In fact, it was titanic, mind-bogglingly amazing woo. We're talking Lionel Mllgrom-grade woo. Actually, we're talking Lionel Milgrom himself, a level of sheer looniness that few, if any, can match, much less surpass. Once you've experienced the sheer power of his quantum homeopathic madness, it's hard not to become…
oracknows | February 4, 2009It's really hard to take David Kirby seriously any more.
Well, actually, it's been hard to take him seriously for at nearly four years now, ever since he wrote his paean to antivaccinationists, Evidence of Harm, in which no conspiracy-mongering related to mercury as an alleged cause of autism was too out there, too ridiculous, for Kirby to parrot. Since then, he's become antivaccine apologist number one, the go-to guy for the antivaccine movement whenever the twisting of science, logic, and reason was needed to spin an event or a study that refutes the "vaccines cause autism" hypothesis. He's…
denialism | February 4, 2009The process of choosing a medical specialty, and applying for residency programs is nearly complete as I have returned from my tour of the West Coast and am nearly done with interview season. This is when medical students travel the country at great (and unreimbursed) expense to find their future training program. When all is said and done, all your research into programs and time spent interviewing boils down to a simple question. Do you want to work with these people for the next 3-7 years of your life?
It's also nice to see the cities where you may live and get a feel for the type of…
clock | February 3, 2009There are 13 new articles in PLoS ONE today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week - you go and look for your own favourites. The Big One today, I'll cover in a separate post a little later, but here I also want to point out a paper by my good friends Elsa Youngsteadt and Coby Schal, back from my NCSU days (Dr.Youngsteadt now works for…
oracknows | February 3, 2009Ten months ago, I thought I was joking. I really did.
Regular readers may (or may not) remember back in March, when, in one of my usual flights of fancy, I decided that I could write a short fictional interlude, a combat scene. True, I didn't do it because I wanted actually to write a fictional story (although I have always wondered if I could write decent short stories or a novel if I put my mind to it). Rather, I did it to make a point, and argument, a reductio ad absurdum, if you will, of a program in the Air Force to bring "battlefield acupuncture" to the our fighting men and women in the…
terrasig | February 2, 2009I've been having this 3:30 am (EST) insomnia for about the last two months, so I often pull the laptop up and survey the blogosphere in the still of the night. A simple look at the Last 24 Hours at ScienceBlogs and elsewhere in the blogosphere tells me that some knuckleheads in the mainstream press have taken issue with Dr Jill Biden, doctor of education, using the honorific, "Dr."
Keep in mind that the article in question comes from the L.A. Times - the very same paper that graces my e-mail account weekly humping their fishwrapper's science and environment coverage. I did just look up some…
dgmacarthur | February 2, 2009Helix Health's Steve Murphy rather breathlessly announces the launch of the Coriell Personalized Medicine Collaborative website (for the uninitiated: you can tell Steve is really excited when he uses five exclamation marks at the end of a sentence rather than four.)
To be fair, it is big news. Coriell is offering a free service - a full genome scan, plus a genetic health report and genetic counselling - that would cost you at least $500 from Navigenics. The pay-off to them is a massive database to mine for new gene-disease associations and information about patient responses to genetic…
palmd | February 2, 2009One of the frequent complaints I hear about real medicine is that it is dangerous. Of course, it's true---so is riding in a train, but it sure beats walking. And that's the danger of this particular fallacy---yes, medicine is a sharp tool, but it's also an effective tool, so we must use it properly. And this is where the tools of evidence- and science-based medicine can give us a hand.
The potential harms of modern medicine must be approached carefully. If they are ignored or approached in an ineffective way, we'll miss an opportunity to save lives. This comment is typical of the type of…
oracknows | February 1, 2009Sometimes, coincidence is a strange thing indeed.
Friday, I wrote this post about yet another meta-analysis whose results are completely consistent with acupuncture being nothing more than an elaborate placebo. Later that day, less than four hours after my post went live, I received this e-mail sent, not to my work account or my other Gmail account, but rather to my account for this blog:
For immediate release
Contact: Karla Shepard Rubinger, Mary Ann Liebert, Inc. (914) 740-2100, ext 2153, krubinger@liebertpub.com
21st Annual Symposium of the American Academy of Medical Acupuncture to Be…
oracknows | January 30, 2009
Sometimes I come across something so bizarre, so utterly wrong, that my mind reels in confusion and amazement, not to mention horror, that anyone can actually think or write something something like it. In fact, for a moment I considered offering up this one bit of horrifically inspired craziness up as an installment of Your Friday Dose of Woo, but I decided against it. The reason, I'm afraid, is the same reason that I've considered some bits of woo previously for this "honor" but then ultimately declined and covered them as normal posts, dripping with my usual brand of Respectful and not-…
oracknows | January 29, 2009I think my title says it all: Can we finally just say that acupuncture is nothing more than an elaborate placebo? Can we?
The reason I ask this question is because yet another large meta-analysis has been released that is entirely consistent with the hypothesis that acupuncture is a placebo. Because I've written about so many of these sorts of studies over the last year or two that I really had a hard time mustering up the will to write about one more. But I got in pretty late last night and therefore knew I could handle this in a reasonably expeditious fashion. Besides, it is a fairly…
palmd | January 28, 2009It's hard to hide severe back pain. When I stand up, I look like a question mark. The visibility of the problem, combined with the general goodness of my fellow human beings, leads to lots of unsolicited advice. Folks have given me great advice (take some NSAIDs, stretch, and don't lay in bed) and some questionable advice (go to the chiropractor, get some acupuncture). My colleagues and I have written a lot about acupuncture. It's sort of a "gateway CAM", in that it has a patina of plausibility. But the evidence of its efficacy has pointed toward it being an elaborate placebo.
To help…
oracknows | January 26, 2009
When I mentioned a while back that, although I like awards as much as the next guy, I don't go actively seeking them, I wasn't kidding. As evidence that I wasn't kidding, I point out that, until some of you started letting me know about it, I had no clue that I had actually won the 2008 Medical Weblog Award for Best Health Policies/Ethics Weblog of 2008. In fact, even though I do peruse Medgaget, the blog that hosts the competition, I had somehow missed the post last Friday announcing the winners.
Of course, it would have helped if the Medgadget guys would have shot me a quick e-mail.
In…
ddobbs | January 21, 2009
My brother, who started his medical career as a pulmonary tech at a naval hospital and is now the medical director for the National Disaster Medical System -- a system that draws heavily on medical personnel normally employed outside government -- sent me this account of his Inauguration Day, which he spent overseeing the NDMS care of the vast crowd on the Mall.
Allen's job that day, for which he spent months preparing, was to be ready for anything from stubbed toes and headaches to widespread medical disasters of the sort best not pondered (except by disaster relief people). The day…
oracknows | January 20, 2009About a year ago, I discussed an article by Dr. Atul Gawande describing a quality improvement initiative that appeared to have been stalled by the Office for Human Research Protections and its apparent tendency to apply human subjects research protection rules to initiatives that are not exactly research using human subjects. The problem appeared to be an excessively legalistic and a "CYA" attitude more than a genuine concern for protecting human subjects. At the time, I was more concerned with the ethical and policy implications of the story rather than the actual research itself. After all…
dgmacarthur | January 19, 2009
Welcome to the 42nd edition of Gene Genie, the blog carnival of clinical genetics and personalised medicine.
Most of the entries in this edition fall under the broad umbrella of personalised genetics, with posts emphasising both the pros and cons of the emerging consumer genetic testing industry.
The promise and perils of personalised genetics
Hsien-Hsien Li from Eye on DNA warned about the potential dangers of pressuring kids to compete in athletic events based on genetic testing results, citing the suicide of a 15-year-old Singaporean boy. Alberto from Medical Pills used Hsien's post as a…