EDAC (Water-Friendly Condensing Agents)

Awhile back, I discussed dicyclohexylcarbodiimide: a condensing agent that helps turn biological monomers (like amino acids) into polymers (like proteins). People use it a lot on peptide synthesizers for this purpose, where the peptides are made in organic solvents. A related compound, EDAC, works in water:

i-0856475a32a34f0dff9652d88ea61c5a-EDAC.png

EDAC works just like dicyclohexylcarbodiimide, but in water. People have used it to, for example, condense short pieces of DNA into longer ones.

I've heard it's a sensitizer (allergen) like DCC, but I'm not sure if it's quite as bad (no vapor pressure, anyway).

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Hi
I woluld like to use this reagent plz let me know the price of the reagent
I want to use this to make an a Primary amide is it is possible ?

And you can remove the urea from your product with a simple acid wash.

By Chemoptoplex (not verified) on 02 Mar 2009 #permalink

I seem to remember reading somewhere that one of the dangers of using EDAC was that exposure to it could lead to depression.