Awhile back, I discussed dicyclohexylcarbodiimide: a condensing agent that helps turn biological monomers (like amino acids) into polymers (like proteins). People use it a lot on peptide synthesizers for this purpose, where the peptides are made in organic solvents. A related compound, EDAC, works in water:
EDAC works just like dicyclohexylcarbodiimide, but in water. People have used it to, for example, condense short pieces of DNA into longer ones.
I've heard it's a sensitizer (allergen) like DCC, but I'm not sure if it's quite as bad (no vapor pressure, anyway).
I woluld like to use this reagent plz let me know the price of the reagent
I want to use this to make an a Primary amide is it is possible ?
And you can remove the urea from your product with a simple acid wash.
I seem to remember reading somewhere that one of the dangers of using EDAC was that exposure to it could lead to depression.
Interesting, i didn't know this had an application in DNA, I'll have to check this out.