cancer

A new analysis of data from the world’s largest and longest-running study of women’s health finds that rotating night shift work is associated with higher mortality rates. The new findings add to a growing awareness that long-term night shift work comes with serious occupational health risks. Published this month in the American Journal of Preventive Medicine, the study found that all-cause and cardiovascular disease-related mortality were significantly increased among women who worked more than five years of rotating night shifts when compared to those who never worked the night shift. In…
America’s petrochemical industry has spent millions trying to discredit the science on benzene, a known human carcinogen linked to leukemia and other cancers, according to an investigative piece from reporter Kristen Lombardi at the Center for Public Integrity. Lombardi begins her story with the life of John Thompson, who spent much of his life working for the petrochemical industry in Texas. She writes: Throughout the 1960s and early 1970s, he often encountered benzene, stored on job sites in 55-gallon drums, which he used as a cleaning solvent. He dipped hammers and cutters into buckets…
Not being Australian and, for some reason, never having encountered her promotion of "natural health" online before, I first encountered Jessica Ainscough, also known as "The Wellness Warrior" over a year ago when I learned that her mother Sharyn Ainscough had died of breast cancer. Her mother, it turns out, had rejected conventional treatment for her breast cancer and chosen instead the quackery known as Gerson therapy. It's a treatment regimen based on long-discredited view of how cancer forms and that requires the consumption of boatloads of supplements and the administration multiple…
New research from the Weizmann Institute of Science reveals that "cells in our brain form little hexagonal grids that keep us oriented, map-like, in our surroundings." Weizmann's resident blogger describes this finding as "a pyrotechnic flash of insight that changes how we understand the brain to work." Game developers delight; this discovery shows "that you can really apply mathematical models to understand how our mammalian brains get their bearings." It may also have immediate implications for understanding human brain disorders such as vertigo. Meanwhile, on ERV, Abbie Smith explores a…
As I've said so many times before, this blog is my hobby. I write about what interests me for my own amusement. If it also interests you, that's awesome. Fortunately, I've found that several thousand people a day do like what I lay down on a daily basis, sometimes with occasional spikes to ridiculous levels of traffic (such as this Dr. Oz post, which for some reason broke all traffic records for this blog since the very beginning, and not by a little bit) and, more recently, this post about how the CDC did not apologize and "admit" that the flu vaccine this year doesn't work, which got…
Five kids in the first trial. Then eleven. Now thirty (ultimately 39): Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia Slowly but surely, HIV genetically modified to genetically modify relapsed acute lymphoblastic leukemia (ALL) patients T-cells are prolonging (saving?) kids lives. Ive written about this treatment a couple times before: ‘Dismal prognosis’ with leukemia? Nothing a GMO virus cant fix. GMO virus vs B-Cell Acute Lymphoblastic Leukemia: Why is this not a standard therapy yet?? Basically, scientists get HIV to teach cancer patients Cytotoxic T-cells how to…
Last week, I discussed a monograph published in the Journal of the National Cancer Institute Monographs entitled Clinical Practice Guidelines on the Use of Integrative Therapies as Supportive Care in Patients Treated for Breast Cancer. As you might remember, I was completely unimpressed. However, those guidelines were not the only thing in that particular JNCI monograph. There were lots of other articles, and, given that some of them show just how deeply quackery has insinuated itself into oncology in the form of "integrative oncology," I thought it was worth revisiting one more time.…
Cancer cure testimonials due to alternative medicine have been a staple of this blog since its very inception. Unfortunately, another staple of this blog since very early on has included stories of children with cancer whose lives have been endangered when their their parents refuse effective cancer therapy for their cancer, in particular chemotherapy. The most recent such story is a particularly depressing one that cropped up last month in Canada. It was the story of an 11-year-old First Nations girl whose parents opted for what they called "traditional" medicine instead of effective…
I happened to have a busy day yesterday, and in addition today's a deadline to submit a letter of intent for a grant application, as well as to write a response to some criticism in a letter to the editor of my recent Nature Reviews Cancer article. (Trust me, it's fun.) Never one to let such an opportunity pass, I decided to take advantage in order to do a little shameless self promotion. A week and a half ago, I gave a talk at Skepticon 7 in Springfield, MO entitled The Central Dogma of Alternative Medicine. It's now been posted on YouTube. Because some of the sound didn't come through as…
Every so often there's an article that starts making the rounds on social media, in particular Facebook and Twitter, that cries out for a treatment by yours truly. Actually, there are more such articles that are constantly circulating on social media that I could work full time blogging and still not cover them all. So I'm stuck picking and choosing ones that either (1) particularly pique my interest; (2) irritate me enough to goad me into action; or (3) reach a level of ubiquity that I can no longer ignore them. I don't think this one's hit #3 yet, but it certainly scores on #1 and #2.…
In a phenomenon known as Peto's paradox, large mammals do not develop cancer more often than small mammals, despite having more cells that could go haywire. On Life Lines, Dr. Dolittle writes "Some researchers suggested that perhaps smaller animals developed more oxidative stress as a result of having higher metabolisms. Others proposed that perhaps larger animals have more genes that suppress tumors." But a new hypothesis argues that large mammals have evolved to minimize the activity of ERVs, which are ancient viral elements integrated into our DNA. Active ERVs can cause cancer and possibly…
It should come as a surprise to no one that I'm not exactly a fan of "integrative oncology"—or integrative medicine, or "complementary and alternative medicine" (CAM), or whatever its proponents want to call it these days. After all, I've spent nearly ten years writing this blog and nearly seven years running another blog dedicated to promoting the scientific basis of medicine, and just this year managed to publish a lengthy commentary in a high impact journal criticizing the very concept of integrative oncology. Unfortunately, it seems to be the equivalent of the proverbial pissing in the…
I figured that yesterday’s post about the First Nations girl in Ontario with lymphoblastic leukemia whose parents stopped her chemotherapy in favor of “traditional” medicine would stir up a bit of controversy, and so it did, albeit much more at my not-so-super-secret other blog, which featured an expanded version of this post. Don’t worry, you didn’t miss anything. It was expanded in order to have a more in-depth discussion of the quack in Florida who’s treating this girl, something I’ve already discussed here and could just link to. Efficiency! Before I launch into this, let me make one…
A few weeks ago, Steve Novella invited me on his podcast, The Skeptics’ Guide to the Universe, to discuss a cancer case that has been in the news for several months now. The case was about an 11-year-old girl with leukemia who is a member of Canada’s largest aboriginal community. Steve wrote about this case nearly a month ago. Basically, the girl’s parents have been fighting for the right to use “natural healing” on their daughter after they stopped her chemotherapy in August because of side effects. It is a profoundly disturbing case, just as all the other cases I’ve discussed in which…
Decreased lung function, breast cancer, miscarriage, depression and neurological disease. These are just a few of the health and disease risks that salon workers disproportionately face while on the job, according to a new report on the impact of toxic chemicals within the beauty and personal care industry. Yesterday, Women’s Voices for the Earth, a nonprofit working to eliminate toxic chemicals from workplaces, homes and communities, released “Beauty and Its Beast: Unmasking the Impact of Toxic Chemicals on Salon Workers,” which highlights decades of research on beauty care workers and…
In the span of just a couple years, five of Heather Buren’s colleagues at the San Francisco Fire Department were diagnosed with breast cancer. At first, Buren thought the diagnoses were part of the unfortunate toll that comes with age. Still, something felt amiss — “it just felt so disproportionate to me,” she said. Around the same time, Buren helped a good friend and mentor within the department as she underwent a double mastectomy. Buren said it was at that moment that she decided to take decisive action. “(The cancer) just brought her to her knees,” she told me. “Now she’s good and back in…
Gayle DeLong has been diagnosed with what she refers to as “autism-induced” breast cancer.” She’s even given it an abbreviation, AIBC. Unfortunately, as you might be able to tell by the name she’s given her breast cancer, she is also showing signs of falling into the same errors in thinking with respect to her breast cancer as she clearly has with respect to autism. As a breast cancer surgeon, regardless of my personal opinion of DeLong’s anti-vaccine beliefs, I can only hope that she comes to her senses and undergoes science-based treatment, but I fear she will not, as you will see. Her…
R.I.P., McKenzie Lowe. Unfortunately, Stanislaw Burzynski was no more able to save you than anyone else, his claims of great success treating pediatric brain tumors notwithstanding: HUDSON — Thirteen-year-old Hudson resident McKenzie Lowe died Friday evening after a 2-year-battle against an aggressive and inoperable brain stem tumor. McKenzie died at 10:27 p.m. in her own bed at her home in Hudson. McKenzie was diagnosed on Nov. 28, 2012 with Diffuse Intrinsic Pontine Glioma, or DIPG, a brain tumor located on the brain stem. Patients with DIPG typically survive for less than a year.…
One of the biggest medical conspiracy theories for a long time has been that there exist out there all sorts of fantastic cures for cancer and other deadly diseases but you can’t have them because (1) “they” don’t want you to know about them (as I like to call it, the Kevin Trudeau approach) and/or (2) the evil jackbooted thugs of the FDA are so close-minded and blinded by science that they crush any attempt to market such drugs and, under the most charitable assessment under this myth, dramatically slow down the approval of such cures. The first version usually involves “natural” cures or…
Supporters of science-based medicine and keeping pseudoscience out of medicine have a few years to prepare for an onslaught of crappy studies “proving” the value of “integrative” oncology. No doubt at this point you’re wondering just what the heck Orac is talking about. I will tell you. It involves an institution we’ve encountered before and a naturopath we’ve met before, specifically the Ottawa Integrative Cancer Centre and Dugald Seely, ND (translation: Not a Doctor), FABNO (translation: Not an Oncologist). Somehow, Dugald Seely and his brother Andrew have somehow scored some sweet,…