influenza
tsmith | January 30, 2007Readers who are regulars at Effect Measure or Deltoid will be familiar with the opinions of attorney and author Michael Fumento. Fumento considers himself an avian flu "skeptic," and recently issued a "challenge" (the title, "My avian flu challenge to the leftist bird-brained squawkers", might give you some clue as to its scientific value) to bloggers, in response to one blogger's comment that "... there was a "50%/50%" chance of [an influenza] pandemic in the next year":
I took advantage of Mr. Paramedic's oversight to bet him 10-1, with him picking the dollar amount, that there would be…
mikethemadbiologist | January 24, 2007Well, kinda sorta. I'm mentioned in a UPI article about rapid diagnosis of influenza and antibiotic use. Rather than repeat the UPI story, here's the abstract (don't worry, I'll translate):
Background: Rapid influenza testing decreases antibiotic and ancillary test use in febrile children, yet its effect on the care of hospitalized adults is unexplored.We compared the clinical management of patients with influenza whose rapid antigen test result was positive (Ag+) with the management of those whose rapid antigen test result was negative or the test was not performed (Ag0).
Methods: Medical…
mikethemadbiologist | January 17, 2007There's an interesting article about the norovirus outbreak in Boston (it also seems to be nationwide). At this point, over half a percent of all the residents of Boston have gone to the emergency room due to this virus--which means even more have been sick.
First, as always, wash your damn hands! Now, onto the public health. What's interesting is that Massachusetts has installed a real-time surveillance system to deal with bioterrorism and biopreparedness (i.e., avian flu--got that, Fumento?). But as the biosecurity 'community'* is beginning to learn, you can't separate biosecurity from…
tsmith | January 8, 2007When people think of Iowa, many of them think of our agriculture (for good reasons). Obviously, it's big business here. We ranked first in the nation in production of corn, soybeans, eggs, and pork in 2005. Indeed, population-wise, hogs here outnumber humans by more than 5 to 1. This is one reason research at our center focuses on zoonotic disease (diseases which can be transferred between animal species), and specifically, diseases of domesticated animals. A story in the news today shows one reason why we study what we do:
Iowa State health officials say someone in eastern Iowa has…
mikethemadbiologist | January 2, 2007So Michael Fumento has issued a challenge to put 'odds' on avian influenza, thinking that somehow I've stated that an avian influenza pandemic is likely (he's also accused me, a scientist, of being "anti-scientist" and "alarmist"). Well, I'm not putting odds down because I've never said that a pandemic is likely. Then again, one should hardly be surprised when a professional conservative completely distorts what one says.
In fact, in the post, I wrote:
We can argue about public health priorities (avian flu isn't my top priority personally).
One would think that was clear, but I made the…
mikethemadbiologist | January 1, 2007From the archives, here's another post about influenza.
...you knew that starting in late September or early October there would be a series of bioterrorist attacks, and that these attacks would kill anywhere from 30,000 - 50,000 U.S. citizens. Now imagine that you could produce a vaccine that would be, at worst partially effective, and at best, completely effective, particularly if enough of the U.S. population were vaccinated. Imagine that, with enough vaccination, thousands of lives could be saved. A competent government, one that could do a heckuva job, would do something, wouldn't it…
mikethemadbiologist | December 31, 2006I've been called out by Michael Fumento regarding a post about avian influenza. While I'm putting that together, I thought it would be a good opportunity to revisit some previous posts about influenza. From the old site:
A think tank in Australia released a report claiming that an influenza pandemic might kill over 140 million people. So, after spending most of my professional career examining the evolution of infectious disease, I think...I don't have any idea if a pandemic influenza strain will evolve. Ultimately, we're trying to anticipate a unique historically contingent event:…
mikethemadbiologist | December 21, 2006Revere, over at Effect Measure, has a solid critique of Michael Fumento's opinion piece about avian flu. What the piece shows is just how ignorant of public health Fumento really is:
1) Many of the necessary steps involved in preparing for a flu pandemic, such as surge production capacity, can be used to produce 'ordinary' flu vaccines.
2) Once a surveillance system is developed, it can be 'repurposed' for other threats as needed. This has happened several times, in different countries.
3) As Revere notes, Fumento's real target is government spending. When will we see Fumento's column…
tsmith | December 21, 2006Ho ho ho, and welcome to the early Christmas edition of Animalcules. Sit back, grab some hot cocoa, and click below to open your Christmas gift of some of the most interesting microbiology-themed blog posts over the past month.
To start us off with, in a new blog to me (the Cornell Mushroom blog), we learn how a fungus assists in the transmission of a nematode from the environment to the host--in this case, cattle. It's a fascinating example of commensalism.
From the same blog comes another post on Batrachochytrium dendrobatidis (or Bd), a fungus which is a cause of skin infections in…
tsmith | December 1, 2006Revere over at Effect Measure has an excellent post linking together the current bird flu situation with John Snow's investigations of 19th century cholera outbreaks. It's an interesting take on the situation--check it out.
mikethemadbiologist | November 5, 2006There is absolutely nothing the Republicans won't politicize. Now, they have launched the War on Vaccination. For a decade, the Robert Wood Johnson Foundation, a foundation dedicated to improving public health, particularly among the poor and the elderly, has funded a "Vote and Vax" program at early voting facilities that serve poor neighborhoods in 24 cities. Basically, if you're over 50, you can get a vaccination at the polling location.
Thursday, in Houston, the Republicans filed a lawsuit to stop this program.
Nevermind that the program has been running for ten years. When the program…
tsmith | October 13, 2006Flu shots are rolling out, and there should be no shortage this year. A few new articles remind the public of the importance of these vaccinations, especially in high-risk groups (something that I touched on here regarding data showing that vaccination during pregnancy can help protect the newborn).
You can find the guidelines for target vaccination groups here. Essentially, it includes anyone immunocompromised or with conditions that make them increasingly susceptible to serious complications of influenza; those 50 years of age and older; and children from 6 months to five years old.…
mikethemadbiologist | October 12, 2006
(from here)
Revere recently had an excellent post about why you should get a flu shot. Let me just add one more reason: the best way to avoid contracting influenza is to be around people who don't have it. While this sounds like something Yogi Berra might say, containing influenza is a group effort. This is a very serious public health problem: the 'ordinary' flu 'only' kills 37,000 people per year. That's right: for every person in the U.S. who dies from AIDS, there are two who die from influenza.
And getting enough people vaccinated, particularly those aged 5-18, could cut the number…
tsmith | October 10, 2006As Revere notes, this week is Pandemic Influenza Awareness Week. I'll have some posts on this after today (still swamped, with no end in sight, unfortunately); in the meantime, check out all the info already available at the Flu Wiki.
tsmith | October 3, 2006I write on a somewhat regular basis on here about vaccines: new research, new shots, addressing skepticism about how well they work or if they're related to autism, etc. Recently, several vaccine stories have been in the news that I've not gotten to yet, so consider this a vaccine meta-post. More after the jump.
The first story is timely in that it discusses the influenza vaccination (and we're heading into that season). Allow me to share an anecdote first. When I was pregnant with my daughter in 1999, I was in graduate school and the lab I worked in was affiliated with a hospital. So…
mikethemadbiologist | October 3, 2006Inspired by this excellent post by Revere about the evolution of influenza, I've delved deep into the archives of the Mad Biologist, and summoned up some evolutionary thoughts of my own about influenza:
I meant to post something about evolution and influenza before my travels up north, but I was swamped by work and couldn't get to it. Thankfully, two colleagues, Carl Bergstrom and Marc Lipsitch, have decided to deal with Wendy Orent's faith-based virology. Orent writes (italics mine):
Indeed, a strictly enforced quarantine could do more harm than good. Herding large numbers of possibly…
tsmith | September 26, 2006I was travelling over the weekend and I'm incredibly busy up through Wednesday, so new material from me will have to wait until later in the week. In the meantime, I'll point you to a stellar post I wanted to highlight last week, from Revere on H5N1 and the evolution ov virulence, and another excellent one from Mike regarding the importance of surveillance when it comes to detecting and containing outbreaks (such as the recent O157 outbreak). He also describes a timeline for how long many of the common procedures take; quite a bit different from what you get watching CSI or similar shows…
mikethemadbiologist | September 25, 2006Do you want to know how to stop, or at least, lessen the next E. coli 0157:H7 outbreak? Improve our surveillance and public health infrastructure.
If we improve the infrastructure, we can speed the response time, making it easier to contain an outbreak.
Let's walk through each of the steps the CDC outlined in its response.
1. Incubation time: The time from eating the contaminated food to the beginning of symptoms. For E. coli O157, this is typically 3-4 days.
There's not much we can do to 'improve' this step. While random testing could be an option, when it comes to produce, I don't see…
mikethemadbiologist | September 25, 2006Most microbiologists, you know, the experts , are not very thrilled with the emphasis being placed on bioterrorism. Inspired by Tara's post on the Bioshield initiative, I'm reposting this from the old site.
This week, leading microbiologists are sending an open letter to NIH stating that the politically-based emphasis on bioterrorism is starving other areas of research. For some time now, I've thought that we've been too concerned with bioterrorism, particularly when good ol' influenza regularly kills 32,000 37,000 people per year (that's one World Trade Center per month for those of you…
tsmith | September 20, 2006 The seventh chapter of Wells' book could be summed up in a single sentence: "biology doesn't need no steeekin' evolution!" Wells argues that, because medicine and agriculture were already doing just fine prior to Darwin's publication of Origin, clearly then, these fields (and others) haven't benefited from an application of evolutionary principles in the time from 1859 to present day, and that Dobzhansky's "nothing in biology makes sense except in the light of evolution" is one big joke.
Wells focuses on medicine and agriculture because these are two fields that we all benefit from, and…