public health
tsmith | April 24, 2007Last summer, I mentioned that groups receiving federal funding were providing misleading information about abortion, including the unsupported statement that having an abortion increases the risk of development of breast cancer. As I noted, this "link" has been refuted by a number of analyses, including a 2004 Lancet paper and a 2003 National Cancer Institute report. As if those weren't enough, a new study comes to the same conclusion: yep, no link. More after the jump.
The new study, appearing in Monday's Archives of Internal Medicine, looked at data from 105,716 women participating in…
mikethemadbiologist | April 23, 2007Tonight, at 6:30pm, at the Boston Public Library, there's a meeting "Preparing Boston Residents for Pandemic Flu." I'm going, but with a great deal of pessimism.
The reason I'm pessimistic, as I've said so many times on this blog, every year roughly 36,000 U.S. residents die from 'ordinary' influenza. We know how to make the vaccine. We could, if we so desired, produce sufficient vaccine. We know whom we should be vaccinating to maximize the vaccine's effectiveness (and, no, we don't routinely vaccinate those people--5 to 18 year olds). And doing all things things would be the needed…
scientificactivist | April 20, 2007On Wednesday, when the Supreme Court upheld a federal ban on "partial-birth abortions" in its 5-4 decision on Gonzalez v. Carhart, it dealt a potentially huge setback to US reproductive freedoms. Although intact dilation and extraction makes up only a small subset of all abortions, this ruling is significant in that it explicitly does not allow for exceptions when the mother's health is at risk. The decision is also notable in its lack of adherence to Court precedence, its lack of reliance on solid legal reasoning, and its ignorance of medical opinion. Much can and should be written about…
mikethemadbiologist | April 19, 2007'E. coli conservatives' is Rick Perlstein's phrase, not mine. After all, the Mad Biologist is quite partial to E. coli; I suppose that makes me an E. coli liberal. Most E. coli, including those isolated from retail meats, are not harmful, so I've always thought the bug gets a bad rap. Only a minority of strains cause intestinal disease (e.g., Shigella), unless they wind up in a place they're not supposed to be, such as the bloodstream or urinary tract. These strains, known as 'ExPEC', which is short for 'extra-intestinal pathogenic E. coli', are only a small, albeit nasty, percentage of…
mikethemadbiologist | April 19, 2007One of the things that has been revealed by the VA Tech shooting is that the government keeps a database of prescription drug users. This has bothered some. Glenn Greenwald writes (italics mine):
Let me ask you this question: let's say I come into your office (I'm a mentally competent adult -- at least in our hypothetical) and tell you that I want to take a Schedule II drug (or Schedule III) for Medical Problem X (or even just garden-variety insomnia, depression, or anxiety). You tell me that I shouldn't, that there is a high risk of addiction, that the problem doesn't warrant that…
tsmith | April 12, 2007It's difficult to believe that it's been over a year since I last wrote a post on the use of masks in the event of an influenza pandemic. Since then, there's been a virtual glut of information out there, and from what I've seen at least, people, businesses, organizations, government, etc. interested in preparation seem to be taking more of a structured approach, rather than a knee-jerk reaction that we saw last year with Tamiflu hoarding and stockpiling masks, which, as I mentioned in the post linked above, have uncertain effectiveness in the event of a pandemic.
I also noted that one big…
mikethemadbiologist | April 10, 2007I've mentioned the National Antimicrobial Resistance Monitoring System (NARMS) before. Today, I'll be attending the NARMS public hearing which is going to discuss four questions:
1) Why, on this night
1) Are there inherent biases in the sampling strategies employed in NARMS? If so, how can they be improved to ensure that the data and interpretation are scientifically sound given current resources?
2) Are there epidemiological and/or microbiological research studies that would better serve the goals of NARMS and the regulatory work of FDA?
3) Are current plans for data harmonization and…
mikethemadbiologist | April 6, 2007A huge number of antibiotic prescriptions are filled due to the misdiagnosis of sore throats. Here's something from the archives about this problem while I'm away.
A long-standing complaint by many microbiologists has been the mistreatment of sore throats in children. Antibiotics are often prescribed even though they are usually ineffective (italics mine):
Most children with sore throats are given antibiotics when they see their doctors, even though a large majority of the ailments are caused by organisms that do not respond to the drugs, a new study has found.
The only common cause of…
mikethemadbiologist | April 4, 2007From the archives comes this post about the effect antibiotic resistance could have during an influenza outbreak.
I recently corresponded with someone in a position to make public health policy who wanted to know what effect antibiotic resistance would have on avian influenza (this makes me think of Kristof's recent column). Since I regularly encounter similar questions, I thought it worthwhile to share this (I've removed other parts that aren't relevant to the matter).
Also, on occasion, I like to demonstrate that the Mad Biologist isn't always Mad...:
Anti-viral resistance. While…
tsmith | April 3, 2007I've given a few talks recently on pandemic influenza. This topic of isolation and/or quarantine hasn't come up frequently during the question-and-answer period, but almost every time I've had someone approach me after the talk to ask about it (since I mention it briefly during the presentation). It seems to be something that really concerns people, and it's a difficult topic. No one wants someone out spreading a deadly disease that could kill you or your loved ones, but at the same time, no one wants to be locked away from their loved ones if they're potentially dying from a deadly…
tsmith | March 30, 2007I don't know if you've seen any of the posts here at Scienceblogs or Panda's Thumb about the Discovery Institute's newest protégé, Dr. Michael Egnor. A professor of neurosurgery at SUNY-Stony Brook, Dr. Egnor has been pontificating on how "Darwinism" has nothing to offer to medicine; and indeed, that evolutionary biology has "hijacked" other fields of study. Mike has already aptly pointed out many of Egnor's strawmen and intellectual dishonesties, so I won't review them all. I've stayed out of the fray until now because I've had limited time and others have been handling it quite ably,…
tsmith | March 29, 2007Influenza season is wrapping up here in the United States, and it seems so far that the 2006-7 season was pretty typical. The first cases of the disease were reported in late October, and cases were sporadic throughout November and early December. After increasing a bit in mid-late December of 2006, outbreaks declined slightly in January, and then picked up again later that month, increasing again in February before falling again, and continuing to do so in March. Early reports suggest that the vaccine matched the circulating strains pretty well, and that most of the isolates which were…
mikethemadbiologist | March 27, 2007One of the few predictable statistics in American public health is that between 35,000-40,000 people will die every year from 'ordinary' influenza. Most of these deaths are preventable. Yet we do nothing.
In the U.S., influenza kills approximately the same number of people every year as breast cancer does. But unlike breast cancer, we don't need to run, walk, jump, pogostick, or unicycle for the 'cure.' All we need to do is vaccinate enough of the appropriate people. It's that simple.
An effective influenza vaccination policy would involve the mass vaccination of those most likely to…
tsmith | March 24, 2007 Mycobacterium tuberculosis infection is as old as civilization. The bacterium infects approximately a third of the world's population--roughly 2 billion individuals. It's estimated that 8 million new cases are contracted each year--around a new infection every second. ~2 million individuals die as a result of TB every year. The bacterium also plays a prominent role in the history of microbiology: it was on March 24, 1882, that Robert Koch announced his discovery of the causative agent of the dread disease tuberculosis:
"If the importance of a disease for mankind is measured by the…
scientificactivist | March 23, 2007
Back in August, I reported on an ACMD study buried in the back of a UK government report. The study gave strong evidence that the current drug classification scheme in the UK was fundamentally flawed and was not based on the actual danger of a given drug. The study has now been published in this week's issue of The Lancet. The Guardian also has a nice piece on it today. The bottom line is that the current unscientific drug classifcations that the UK (and the US) currently rely on need to change. Now.
Here's what I originally wrote:
(1 August 2006) Yesterday, the House of Commons…
mikethemadbiologist | March 19, 2007
Yum. Theological conservative tastes GOOOODDD!
Full disclosure: I have never bought into the belief of the Compulsive Centrists that John McCain is a moderate. A detailed look at his voting record shows that he is often very conservative, with the occasional moment of lucidity (e.g., recognizing that global warming is actually happening). But it is truly pathetic to watch a man who clearly doesn't agree with the theological conservatives twist himself into a pretzel in an effort to placate them. He's done it with evolution. Now, he is 'confused' about condoms:
The unthinkable has…
scientificactivist | March 17, 2007Not that HIV/AIDS is an important issue or anything... but it appears that Republican presidential hopeful John McCain hasn't been thinking much--or at all--about HIV prevention. The New York Times blog The Caucus reports that when asked about the subject at a recent campaign rally in Iowa, McCain looked completely stumped:
Did he support the distribution of taxpayer-subsidized condoms in Africa to fight the transmission of H.I.V.?
What followed was a long series of awkward pauses, glances up to the ceiling and the image of one of Mr. McCain's aides, standing off to the back, urgently…
mikethemadbiologist | March 15, 2007
To prevent brain damage, the Surgeon General recommends that statements by Michael Egnor be read using approved devices such as the StupidView9000
Orac bravely dives deeper into the Discovery Institute's creationist drivel, and reports on the continuing ignorant idiocy of Michael Egnor. I don't know what's worse: Egnor's willful ignorance, or his pseudo-victimization complex. Let's deal with the ignorance first.
In an interview with Casey Luskin, Egnor states (italics mine):
EGNOR: Well, it's a pretty funny claim on the part of Darwinists. It's sort of like Al Gore claiming that he…
tsmith | March 14, 2007The most recent edition of Tangled Bank, your one-stop science blogging carnival, is up over at Living the Scientific Life.
In addition, there are a few other posts I've been meaning to plug:
Nick on Texas House overturning mandatory HPV vaccination.
Burt at Panda's Thumb on Why you should care if cattle get fourth-generation cephalosporins and why doctors need to know about evolution (a takedown of this Discovery Institute essay).
And a nice follow-up to those: Mike on why antibiotic resistance matters.
scientificactivist | March 13, 2007The Texas House voted today 119-21 to overturn governor Rick Perry's executive order requiring mandatory vaccination against HPV (human papilloma virus) for girls entering the sixth grade. The bill, HB1098, still requires final approval in the House before moving along to the Texas Senate. Perry could attempt to veto the bill, but his veto could be overridden with a two-thirds majority in both the House and the Senate. The House demonstrated today that it already has the necessary votes to counter a veto.
The House bill takes things a step further by preventing the adoption of any HPV…