Nobel Prize for Medicine/Physiology

As you have probably heard already, Andrew Fire and Craig Mello have won the Nobel Prize in Medicine for the discovery of RNA interference.

Jake Young explains what RNAi are and what they do and why is this so revolutionary. Then he explains why those two people got the Nobel for this work instead of some others.

Alex Palazzo (also here), Abel PharmBoy, Carl Zimmer, Nick Anthis and PZ Myers have more and explain it much better than I could ever do. The last time the Nobel was given for work I really understand and like was in 1973 - ah, the good old days when the Nobel did not require molecular biology!

Anyway, this is the first time a Nobel was given for something that was discovered at the time when I was already in the lab and I remember the rumors about it around the molecular labs in the Department. Usually it takes decades for the finding to get a Nobel (and in my field, all the "founders" are dead by now), so this was really fast - indicating how important it is.

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Best as I can tell, our resident MD/PhD student, Jake Young at Pure Pedantry, was first to post on this morning's announcement. The Nobel Prize website has a very nice press release on why the discovery of RNA interference is so central to our understanding of biology and is likely to result in…
Andrew Fire and Craig Mello have won the Nobel Prize in Medicine for the discovery of RNA interference: Americans Andrew Z. Fire and Craig C. Mello won the Nobel Prize in physiology or medicine Monday for discovering a powerful way to turn off the effect of specific genes, opening a new avenue for…
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Emil Adolf von Behring was the first person to receive the Nobel Prize in Physiology or Medicine, for his work on the treatment of diphtheria.