Medicine
clock | October 22, 2009Open Access Week is in full swing and there is a lot of blogging about its various events in many countries.
OA week was marked in Serbia this year as well. As you may remember, I went to Belgrade twice in the past two years - in 2008 and 2009 and gave a total of four lectures, one brief TV interview, four long radio interviews and a print interview. I am now writing a paper about Open Access for one of their journals as well.
This effort has paid off.
I have remarked before how difficult it is to make changes in smaller countries - the scientific community is small, everyone knows everybody…
revere | October 22, 2009A reader (h/t MVD) sent me this link to a "CBS News Exclusive," Study Of State Results Finds H1N1 Not As Prevalent As Feared. As far as I can see the main aim was to raise CBS News's profile and gain readership. That's what news organizations do. We hope they do it by good journalism. I think this is an example where the reporters just didn't have enough knowledge of what they were reporting and put the wrong spin on it.
The central claim is that CDC stopped testing for swine flu hastily and without advance notice to the states:
If you've been diagnosed "probable" or "presumed" 2009 H1N1 or…
edyong | October 20, 2009This is the story of a Turkish boy, who became the first person to have a genetic disorder diagnosed by thoroughly sequencing his genome. He is known only through his medical case notes as GIT 264-1 but for the purposes of this tale, I'm going to call Baby T.
At a mere five months of age, Baby T was brought to hospital dehydrated and in poor health. In some ways, this wasn't surprising. His parents were blood relatives and they had suffered through two miscarriages and the death of one premature baby. Baby T himself was born prematurely at 30 weeks.
Baby T's family history suggested that he…
scientificactivist | October 19, 2009Late last week, I received emails from two journals (The Journal of Biological Chemistry (JBC) and PLoS ONE) indicating that they are now incorporating interactive 3D images of molecular structures in their papers. The atomic coordinates of all published biomolecular structures have been available for some time at the Protein Data Bank. However, making sense of something as complex as a protein structure can require quite a bit of analysis. So, scientists go through great pains to represent important features of their structures in 2D images for publication. Ostensibly, this new functionality…
revere | October 18, 2009We've been traveling again (and offline), so we'll limit this to a few comments to put recent news into the context of things we talked about here recently (an excellent up-to-date status report can be found by DemFromCT at DailyKos). A good article by Rob Stein of the Washington Post highlighted some of the increasing anxiety of clinicians as flu season ramps up with pandemic swine flu in the northern hemisphere. Stein's article is quite long, but I have snipped a few things from it:
Although why a minority of patients become so sick remains a mystery, new research indicates that H1N1 is…
grrlscientist | October 17, 2009The good news is that things are really falling into place now -- something I thought would never ever happen.
First, I walked through icy winds and a light dusting of snow to bring my ailing lory to my veterinarian, Simon Starkey, on Thursday morning to get blood drawn so they could look again to see if she's diabetic. The blood tests came back Friday morning, showing that she had blood glucose levels that were twice the normal values, which is something that can result from stress or from mild diabetes. Since she was so ill when I initially brought her in (yay, for poverty for making me…
oracknows | October 16, 2009I'm back.
If there's one thing I've noticed in the nearly five years that I've been doing this blog thing, it's that getting started again after taking even a few days off is hard. There's a bit of paralysis that sets in. I get used to not having to think about what I want to write, and often there are a number of things that I almost certainly would have written about. Fortunately, for at least one of them, PalMD took care of it it for me. Otherwise, the blogger whose post he deconstructed would have tasted a bit of the ol' not-so-Respectful Insolence for in essence laying down a load of po-…
oracknows | October 15, 2009As I mentioned on Friday, I'm in Chicago right now attending the American College of Surgeons annual meeting, where I was until last evening. Unfortunately, I got back too late and was too tired to lay down some fresh Insolence, Respectful or otherwise. Fear not, though. I'll get to it. In the meantime, here's a blast from the past from the past. This post first reared its ugly head almost exactly three years ago; so if you haven't been reading at least three years, it's new to you.
By the way, even though this post is three years old, the problem described in it has only gotten worse in the…
gsmith | October 12, 2009
Below, Josh Ruxin answers our final question.
Hands down, the application of private sector management solutions to health care, particularly in developing countries, is vital, and, almost utterly unfinanced. The focus of public health systems continues to be on training and retraining personnel, and identifying gaps in specific administrative systems. There's a raft of research on drug procurement systems, billing systems, and electronic patient medical records. The industry has come to resemble the three blind men each touching a different part of the elephant and trying to describe…
gsmith | October 11, 2009
Below, Moshe Pritsker answers our final question.
Genomics is a good example of a cross-disciplinary approach that produced a landmark shift in biomedical research, drug discovery, and other life science areas. Enabling single experiments that produce amounts of data that would require thousands or millions of experiments just a few years ago led to a drastic increase in the information on biological and medical molecular-level processes. Genomics has changed the technical foundation of biomedical sciences and strongly reshaped the conceptual thinking in this field. The changes introduced…
emjohnson | October 10, 2009
In the classic film Casablanca, the drama hinges on Ilsa's choice between two men: her kind and supportive husband or her rugged and passionate ex-lover. In a moment of abandon, Ilsa returns to her lover's arms only to later change her mind and choose the more stable life she would have with her long-term partner. But what if something as simple as a pill had caused Ilsa to feel differently and make the opposite choice?
In a new paper in the journal Trends in Ecology and Evolution biologists Alexandra Alvergne and Virpi Lummaa at the University of Sheffield in England raise the possibility…
oracknows | October 8, 2009Quackademic medicine has struck again. Worse, it's struck at one of my old stomping grounds. OK, not exactly, but rather close to a past home.
Let me back up a minute.
I know someone who attended nursing school at UMDNJ. It's actually a very good nursing school, but, alas, it has a serious woo streak in it. Yesterday, because of that connection, I was shown a pamphlet that had arrived in the mail. It was a the Continuing Education Catalog for the UMDNJ School of Nursing. At first glance, it looked pretty unremarkable. There were the usual courses in subjects like trauma nursing, clinical…
palmd | October 7, 2009One of my bibles of clinical medicine is Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology. It's basically a field guide to skin, with hundreds of pictures matched up with brief summaries. The introduction states, "We have endeavored to include information relevant to gender dermatology and a large number of images showing skin disease in different ethnic populations." The book devotes a section on each disease to racial differences. For example, the section on superficial spreading melanoma (p. 312) states that "white-skinned persons overwelmingly predominate. Only 2% [of…
revere | October 7, 2009This is the internet. Like the newspaper, you shouldn't automatically believe everything you read on it, and when it comes to some of the more outlandish stuff, most people don't. But there are a lot of sites that appear quite legitimate, and maybe for some of the material on them they are fine, but sometimes mixed in is some real dangerous stuff. One genre we know is influential and a major source of information is what is sometimes called a "Mommy Blog," blogs or websites that cater to the insatiable hunger for reliable information of newly pregnant women or new moms. We wouldn't have…
oracknows | October 6, 2009Alright, I think I got the whole Maher/Dawkins thing out of my system for now. True, given the highly annoying reaction of one reader, I was half-tempted to write yet another post on the whole fiasco just out of spite, but I decided that spite in and of itself was not a good reason to write a blog post. Well, in this case it isn't, anyway, but if it were someone like Vox Day, or J.B. Handley, or a hapless quack or creationist, well, a wee bit of spite can make for some mighty fine blogging that's really fun to write. True, spite should never be the be-all and end-all of a blog, but certainly…
dgmacarthur | October 6, 2009Things are as usual moving at ludicrous speed in the world of genomics, but sadly I only have time to post a few pointers to some of the most striking developments.
IBM is moving into the third-generation sequencing arena. The company is developing a new sequencing technology based on tiny nanopores - a field already being explored by the understated British nobility of sequencing, Oxford Nanopore. This is all over the news, but Dan Vorhaus has an introduction and is promising to follow up on further developments. You can also watch a pretty but largely content-free animation of the process…
clock | October 2, 2009Let's check all seven PLoS journals today. As always, you should rate the articles, post notes and comments and send trackbacks when you blog about the papers. You can now also easily place articles on various social services (CiteULike, Mendeley, Connotea, Stumbleupon, Facebook and Digg) with just one click. Here are my own picks for the week - you go and look for your own favourites:
Circadian and Social Cues Regulate Ion Channel Trafficking:
Excitable cells, such as neurons and muscle cells, control behavior by generating action potentials, electrical signals that propagate along the cell…
oracknows | October 1, 2009
The endgame is in sight. At the end of this post is a list of questions for Bill Maher tomorrow (if the opportunity presents itself), the vast majority of which you, my readers, thought of.
Let's backtrack a minute.
A couple of months ago, I learned that an award named after Richard Dawkins was being given to someone who was so radically, unbelievably unworthy of such an honor, that I likened giving the Richard Dawkins Award to Bill Maher to giving a public health award to Jenny McCarthy. (In deference to Professor Dawkins, perhaps I'll now liken it to giving such an award to MMR anti-…
revere | September 30, 2009For the first time in medical history we may be seeing an influenza pandemic unfold in real time, but that doesn't mean we know what we are seeing. There remains some uncertainty about virulence, both in terms of how often it kills and how it kills when it does kill. You'd think both would be easy to determine, but those who have been following along know the problem of how often infection with this virus kills is made almost impossible by not knowing how many people it is infecting. But what about the question of how it kills? There are mainly three scenarios of interest: primary viral…
terrasig | September 29, 2009When writing the other day about how blogging has been of benefit to my career, I neglected to mention my recent invitation to the board of Science Communicators of North Carolina (SCONC).
Founded in June 2007 by Karl Leif Bates and Chris Brodie, and now headed by President Ernie Hood (Radio In Vivo), SCONC is a group of "science writers, journalists, public information officers, teachers and institutional communicators from academia, government labs, industry, museums and schools -- just about anyone interested in communicating science," who aim to improve public understanding of science…